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Therapeutic areas
Where we focus
Therapeutic area
Oncology
Targeted medicines and antibody–drug conjugates for hard-to-treat solid tumors and blood cancers.
4medicines5pipeline programs6open trials
Therapeutic area
Immunology
Precision biologics that calm overactive immune pathways in skin, gut and joint disease.
4medicines4pipeline programs5open trials
Therapeutic area
Neuroscience
New approaches to neurodegeneration, migraine and mood disorders, guided by human genetics.
3medicines3pipeline programs5open trials
Therapeutic area
Cardiometabolic
Long-acting therapies for heart failure, lipid disorders and metabolic disease.
3medicines3pipeline programs4open trials
Therapeutic area
Rare Disease
Gene and RNA medicines for small patient communities with no approved options.
2medicines3pipeline programs4open trials
Our approach
How we pick what to work on
01Human geneticsStart from genes and pathways proven to matter in people.
02Target validationConfirm the biology in patient samples before we build a drug.
03Right modalityPick the molecule type that best fits the target and the patient.
04Clinical proofUse biomarkers to show early that a medicine is working.
Modalities
The right tool for each target
6AntibodyCLV-114, CLV-205, CLV-219, CLV-226, CLV-302, CLV-419
6Small moleculeCLV-101, CLV-131, CLV-158, CLV-211, CLV-310, CLV-318
4RNACLV-325, CLV-404, CLV-427, CLV-515
3Gene therapyCLV-501, CLV-508, CLV-522
2ADCCLV-122, CLV-147
1BispecificCLV-140
1Cell therapyCLV-233
1PeptideCLV-412